With a call that could be mistaken for a birdcall, the Gray Tree Frog makes a lovely sound. Their trilling occurs not only during mating season, but at all times of the year. The Gray Tree Frog is fascinating to observe in the wild or in captivity.

Gray Tree Frogs are arboreal and nocturnal. Their calls are quite common in the norther United States and Canada. They can be quite loud. They will often come down to the ground from the trees in order to locate food. They search in vegetated areas for things such as plant lice, spiders, snails, and mites. Most often, Gray Tree Frogs are found high in trees. Outside of their breeding season, they may be more difficult to find. Because they require water to breed, Gray Tree Frogs usually make their homes in forests near permanent bodies of freshwater. They hibernate in winter, buried beneath a tree root or dead leaves. Gray Tree Frogs are quite territorial, especially during the breeding season. Males use calls to maintain a range, and may kick or shove intruders out of their homes. The call sounds much like that of a bird, and is a sort of trilling or chirping noise. As with all tree frogs, Gray Tree Frogs can stick to most everything. It is not unusual for them to be seen climbing the glass of their enclosures, or even sleeping stuck to the sides of their cages. They can also hang upside down from the screens, which cover their cages, so care should be taken when opening their tanks. It has been reported that this frog responds well to hand feeding. This makes them easier to move because they are more used to their keepers.

Named rather inappropriately, Gray Tree Frogs may actually be green, brown, or white, although some are gray. In fact, depending on the frog's stress level or environmental stimuli, it may change color slightly. There may be several blotches of a darker color over the frog's back, and the insides of the thighs are usually washed in a light orange-yellow color. Under the eyes, often a lighter spot outlined with a darker color is evident. Usually, Gray Tree Frogs grow to a length of 1 to 2 inches (2.5 to 5 centimeters). The skin, especially over the back, is warty and textured. Very large toe pads are evident, which help Gray Tree Frogs to climb trees and bushes.

Gray Tree Frogs are most often found from southern Ontario in Canada down through the United States to its southern coast. The range includes more westward areas, but generally does not extend west of Texas in the United States or Manitoba in Canada. Gray Tree Frogs are common in their ranges, but, like all amphibians, may be adversely affected by water pollution.

Gray Tree Frogs can be kept in vertically oriented terrariums with well-established plants or bamboo stands, although horizontal climbing opportunities are also advisable. The lid should be quite secure as these frogs are good climbers. The terrarium should be maintained at about 80 degrees Fahrenheit during the day, and the nighttime temperature should be about 68 to 70 degrees Fahrenheit. Daily misting is advisable. A mixture of potting soil, playground sand, and cypress can be used as substrate. Gray Tree Frogs should be fed small insects like crickets, small grasshoppers, waxworms, butterworms, and superworms.

Gray Tree Frogs usually reach sexual maturity by the time they are three years old. Males may be distinguished from females by their calling activity. The breeding season usually occurs between May and August (this varies depending on location), and eggs are laid attached to floating vegetation in shallow water. Many bundles consisting of 10 to 40 eggs are laid until about 2,000 eggs have been deposited. These hatch in about five days.